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This cross-sectional study examines the prevalence and risk of mental disorders, substance use disorders, and suicidal behaviors among transgender and gender-diverse (TGD) and cisgender Canadians.

This cross-sectional study uses national vital statistics on firearm mortality to investigate trends in firearm deaths among youths in the US, Brazil, Mexico, and Colombia.

This cohort study assesses changes in the incidence and prevalence of clinically diagnosed depression and anxiety without depression among US children, adolescents, and young adults aged 5 to 22 years from 2017 to 2021.

This cohort study examines cognitive function in middle-aged adults with hearing loss, both with and without use of hearing aids.

This economic evaluation estimates the lifetime cost-effectiveness of implementing a structured education and therapy program for knee osteoarthritis in Australian adults.

This cohort study assesses the magnitude of cancer registration delays and their estimated affects on the NordICC trial results assessing the long-term effects of screening colonoscopy in preventing colorectal cancer.

This cross-sectional study investigates the association between glucagon-like peptide-1 receptor agonists and food retention during esophagogastroduodenoscopy.

This cross-sectional study examines the recommendations and agency actions of temporary and permanent US Food and Drug Administration advisory committee members from 2017 to 2021.